Nuclear Matrix Protein SMAR1 Represses c-Fos-mediated …

Nuclear Matrix Protein SMAR1 Represses c-Fos-mediated …

Results: Curcumin-induced SMAR1-HDAC1 recruitment at LCR and E6 region on E6 promoter deacetylates chromatin histones to attenuate c-Fos-mediated E6 transcription to reinstall p53-mediated apoptosis in HPV18-infected cervical cancer. … Matrix attachment region (MAR)-binding proteins have been implicated in the transcriptional regulation of host as well as viral genes, but their precise role in HPV-infected cervical cancer remains unclear. Here we show that …

(Visited 2 times, 1 visits today)
11
Like
Save

Comments

Comments are disabled for this post.